T cell Take Down: Researchers discover how cancer cells manipulate the immune system

Harvard Medical School
Harvard Medical School
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Published 2022-10-24
A team led by researchers at Harvard Medical School has identified a way that tumor cells can turn off the immune system, allowing the tumor to grow unchecked. The research, conducted primarily in mice and published Sept. 29 in Science, shows that tumor cells with a particular mutation release a chemical, a metabolite, that weakens nearby immune cells, rendering them less capable of killing cancer cells.

Version that includes an audio-description:    • T-Cell Take Down (with audio descript...  

Learn more: hms.harvard.edu/news/disarming-bodys-defenders
All Comments (12)
  • @abdelrahmanatef7426
    I just studied cd-8 receptors in advanced level biology and that helped alot!
  • @superuser8636
    Finally, I can say I’m Harvard Medical School educated
  • @stephanedubedat5538
    Agreed with the other comment. You could afford to put less work/emphasis on the animation work but should provide more information about the topic. E.g no quantification of damage is done here. No talk about developing antigens that target this protein, etc
  • @bingeltube
    The video is too short to cover the subject! Such a video should be at least 5 minutes long to give more background etc. This video contains almost less information than a typical research paper abstract. Quite an achievement!
  • @josephmoses4902
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  • @teemunator
    So could D-2HG be used to suppress rejection of an organ transplant? Also could D-2HG intake be blocked on T cells as a part of cancer prevention and treatment?
  • @CarlosCruz-rp6jm
    Drinking natural spring water and taking cold showers and help your immune system I’ve heard.
  • @Abigail-rl1hb
    I thought my body would never be the same again, but you fixed it. My heartiest gratitude to you Dr Igudia for helping me cure my Genital Herpes virus successfully.