Cushing Syndrome, Causes, Signs and Symptoms, Diagnosis and Treatment.
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Published 2020-08-03
Chapters
0:00 Introduction
1:10 Causes of Cushing
2:58 Symptoms of Cushing
4:15 Diagnosis of Cushing
4:47 Treatment of Cushing
Cushing's syndrome is the collection of signs and symptoms due to prolonged exposure to glucocorticoids such as cortisol.[3][8][9] Signs and symptoms may include high blood pressure, abdominal obesity but with thin arms and legs, reddish stretch marks, a round red face, a fat lump between the shoulders, weak muscles, weak bones, acne, and fragile skin that heals poorly.[2] Women may have more hair and irregular menstruation.[2] Occasionally there may be changes in mood, headaches, and a chronic feeling of tiredness.[2]
Cushing's syndrome is caused by either excessive cortisol-like medication such as prednisone or a tumor that either produces or results in the production of excessive cortisol by the adrenal glands.[10] Cases due to a pituitary adenoma are known as Cushing's disease, which is the second most common cause of Cushing's syndrome after medication.[3] A number of other tumors may also cause Cushing's.[3][11] Some of these are associated with inherited disorders such as multiple endocrine neoplasia type 1 and Carney complex.[7] Diagnosis requires a number of steps.[4] The first step is to check the medications a person takes.[4] The second step is to measure levels of cortisol in the urine, saliva or in the blood after taking dexamethasone.[4] If this test is abnormal, the cortisol may be measured late at night.[4] If the cortisol remains high, a blood test for ACTH may be done.[4]
Most cases can be treated and cured.[6] If due to medications, these can often be slowly decreased if still required or slowly stopped.[5][12] If caused by a tumor, it may be treated by a combination of surgery, chemotherapy, and/or radiation.[5] If the pituitary was affected, other medications may be required to replace its lost function.[5] With treatment, life expectancy is usually normal.[6] Some, in whom surgery is unable to remove the entire tumor, have an increased risk of death.[13]
All Comments (21)
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Worst time of my life before diagnosis! Took 2 years to get it! Gained 80 lbs, moon face, buffalo hump, skin thinning, headaches, sleep disturbances, blood pressure 200/100 ( put on 5 meds, still high)! Was told just getting older 😮 finally diagnosed self with Cushing and demanded testing! Raging Cushings! Large tumor on adrenal gland. Had it removed along with partial kidney removal. Do not give up, keep searching for answers. Have never felt completely cured but tons better!
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I am 3 years in remission of cushings syndrome.. if are experiencing any of the symptoms mentioned PLEASE get it checked immediately out to eliminate any long term threats
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this is so informative. this might explain everything for me
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Thanks for the video
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Awesome explaination
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Thanks for your information
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Your animations are amazing. Do you creat them?
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Thank you for your excellent video explaining Cushing 🙏❤️
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Good effort keep it up
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Omg, is this my solution after 49 years of suffering?
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As someone who has been on heavy steroids for 16 years straight and has a hump i am intruiged
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Could you share sources or articles used in this video, please.
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hey, pharmacy student here, could you share your sources? I have to do an assignment about cushings but the teacher is 1 week late on the theory classes so i'll only have this class after i have to submit the assignment, and the class is where the teacher send us links and articles for us to read
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I think i have Cushing syndrome bcz i have buffalo hump. Is exercise and diet can help to fight with this disease ?
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I'm wondering about something. If I could get some advice. I am having a blood cortisol test AM and PM. If i come home after the AM test and sleep for 2 hours, would that affect the PM test results? Thanks for any help that could be offered
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I need to see a doctor ASAP
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Could you share your animations?
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5:17 pleaseeee someone explain i dont get it how glucocorticoids medications are used in suppressing the disease
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I think i have this.. terrible terrible fatigue ,hairloss and weight gain..but i dont have the buffalo hump. my cortisol is high at 8am..how do i know if its in my brain or adrenals? Thyroid antibodies High and i also have insulin resistence.
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I have many symptoms specifically high blood pressure and kidney pain and irritability with severe weight gain and retinal vein occlusion
