Folate Deficiency, Causes (ex. medications), Pathogenesis, Symptoms, Diagnosis and Treatment

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Published 2019-09-14
Lesson on Folate Deficiency: In-Depth Overview of the Causes, Pathogenesis, Signs and Symptoms, Diagnosis and Treatment. Folate (or Vitamin B9) is an essential water soluble vitamin that is necessary for red blood cell development and maintenance, due to it being required in nucleic acid synthesis. There are several categories of causes of folate deficiency including reduced dietary intake, malabsorption, impaired metabolism, and increased utilization. In this lesson, we discuss in detail the many causes within each of these categories. We also discuss the classic signs and symptoms of folate deficiency, the characteristic findings on laboratory investigations, how to diagnose and what we do to treat folate deficiency. We also discuss why folate is important during pregnancy, specifically with regards to neural tube development.

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All Comments (21)
  • I have chronic folate deficiency and one of the main symptoms I experience is low mood. When my folate levels are good I feel mentally very well, I don’t have depression or low mood or anything like that, but when my folate is low, my mood is low.
  • @Zetsuke4
    Please post more videos! I love your teaching style so much. The most effective format I have seen on YouTube honestly
  • @emilywood6830
    A medication I wish you included was the hormonal birth control pill which decreases many key vitamins, including B12 and B9
  • @24carrotgold8
    MTHFR defect runs in my family. Unfortunately my niece got the defect from her father's side as well. A genetic savvy doctor prescribed Thorne Methyl Guard prior to pregnancy and she carried twins almost to full term. Mark was 5 lbs and Penny was 2.9 lbs. Autopsy on Penny's umbilical cord showed a missing artery. After 3 weeks in NICU she came home and overcame digestive issues and is now a thriving child. Her little sister born 2 years later had a normal development because my niece continued with the supplementation.
  • @cricket700612
    Excellent video! Thank you! Precise and instructive.
  • @Frommel2000
    0:20 Folate does not come from fortified grains. Fortified grains contain folic-acid which can be harmful when taken long term.
  • @dianarhyne
    Folic acid form is in fortified foods, like grains and cereals. This form is harder for many people to use. It can actually do more harm. Folate form is best.
  • @User-to7nb
    This is my lesson today. HOW DID YOU KNOW?!
  • @caroline61804
    If you lack methylation correct it via supplementing with B2 first. Add B9 aka folate and B12 after like a week of supplementing with B2
  • @FLgardener67
    My Doctor has me on Folate, B- complex and B 12 supplements due to having MTHFR mutation. Can you update your video's highlighting this. Thank you
  • @hasanshokor3255
    Thank you very much love your videos, hope more terms 🌾☘🌱💐
  • My wife has the MTHFR gene and has always had nausea in the morning. It was worse when pregnant. We have three children. The first and last were supplemented with folate but for the second she used *folic acid*. The second was the only to have a tongue tie and after using methyl folate she no longer is nauseous in the morning. This is just FYI. Who knows if it is a coincidence.
  • Can you update this video series for folic acid and furin in covid?
  • very good presentation. I have just been diagnosed with severe folic acid deficiency. I have been on sodium valporate for epilepsy for the last 20 years and never did any Dr recommend any supplementation until the last week when i started to suffer from severe tiredness and feeling dizzy at which point a blood test showed the deficiency.
  • @ZerHour
    I believe there's a growing link with folate issues and the CV virus ,I got the virus and it wiped out my folate big time ,still undergoing treatments
  • @user-zk8ed4kd2b
    Would you include plaque psoriasis as one of the exfoliative skin conditions?